Table 3 Nanoparticle formulation containing natural bioenhancer
Nanoparticle formulation | Bioenhancer | Application | Preparation method | % of entrapment efficiency | Biological activity | Mode of administration | Ref |
|---|---|---|---|---|---|---|---|
Nanocapsules of artemisinin | Artemisinin | Long-term medication release | Layer-by-layer technique | 90–93 | Anticancer | In vitro | [37] |
Nisoldipine-piperine nanoparticles | Piperine | Improve bioavailability | Precipitation method | 89.77 | Calcium channel blocker | Oral | [38] |
Isradipine-rutin nanoparticles | Rutin | Enhanced systemic bioavailability | Homogenszation by the ultra-sonication method | 97.85 | Hypertension | Oral | [39] |
Amphotericin B-piperine nanoparticles | Piperine | Enhanced bioavailability | Solvent evaporation method | 48 | Antileishmanial activity | Oral | [40] |
Paclitaxel-piperine, quercetin nanoparticles | Piperine, Quercetin | In comparison with free paclitaxel, it has greater solubility and bioavailability | Solvent evaporation method | 56.12 for Piperine 58.97 Quercetin | Anticancer | Oral | [41] |