Antidiabetic activity of mango peel extract and mangiferin in alloxan-induced diabetic rats

Future Journal of Pharmaceutical Sciences

Table 2 Effect of mango peel extract and mangiferin on fasting plasma glucose level in the alloxan-induced type I diabetic rat

Days	Control (Tc) (mg/dl)	Alloxan (Ta) (mg/dl)	Alloxan + extract (Tae) (mg/dl)	Alloxan + mangiferin (Tam) (mg/dl)
0	87.16 ± 1.22	285 ± 6.13	312.83 ± 11.02	314.83 ± 10.83
7	86.33 ± 1.08	286.83 ± 6.77	233 ± 10.89	221 ± 7.67
15	83.5 ± 1.28	310.5 ± 4.16	137.83 ± 4.16	136.33 ± 2.66
21	85.83 ± 1.19	308.83 ± 6.09**	88.5 ± 1.80^#	91.16 ± 2.54^#

Values are mean ± SEM (n = 6); *Significant at 5% level, **Significant at 1% level and ^#Not significant
The fluctuations in body weight in different groups are stated in Table 2. Ta group has higher blood glucose levels and is significantly different (p < 0.01) than the control group (Tc). Plasma glucose levels are similar in the other groups as they are in the control group, and there was no significant difference