Time (min) | Ranolazine (50 μM) | Ranolazine (50 μM) + verapamil (10 μM) | Ranolazine (50 μM) + verapamil (50 μM) | Ranolazine (50 μM) + verapamil (100 μM) | Ranolazine (50 μM) + verapamil (200 μM) |
---|---|---|---|---|---|
10 | 9.35 ± 0.94 | 10.72 ± 0.83* | 13.54 ± 1.36* | 16.69 ± 1.54* | 16.01 ± 0.97 |
20 | 14.02 ± 0.83 | 18.08 ± 0.79* | 21.24 ± 1.71* | 24.73 ± 1.24* | 25.82 ± 1.88 |
30 | 21.12 ± 1.45 | 23.26 ± 1.22* | 25.66 ± 1.20* | 25.77 ± 3.31* | 28.35 ± 1.96 |
40 | 20.83 ± 1.24 | 24.58 ± 0.95* | 28.17 ± 1.14* | 30.98 ± 1.87* | 32.11 ± 1.7 |
50 | 20.58 ± 1.35 | 27.00 ± 0.88* | 29.9 ± 1.81* | 32.51 ± 1.19* | 33.11 ± 1.36 |
60 | 20.31 ± 1.56 | 27.98 ± 1.03* | 31.04 ± 1.87* | 36.47 ± 1.38* | 37.21 ± 1.15 |