Table 4 Ethnomedicinal use, validation, antimicrobial activity and main phytochemical constituent of selected M. indica parts
Antimicrobial activity | Use in ethnic medicine | Experimental validation | Possible phytochemical | Related formulation |
|---|---|---|---|---|
Antibacterial | Mango kernel, seed and leaves are used in treatment of wounds and boils in Asia and Africa | Bshabshe et al., [23] investigated the antibacterial activity of ethanol extract of mango kernel on clinical isolates of S. aureus and MRSA | Topical gel [51] | |
Antifungal | Mango leaves decoction are taken orally and applied on affected areas | Disegha and Akanni [28] conducted a study on the antifungal property of M. indica leaf extract on Aspergillus fumigatus, A. flavus, A. niger and C. albicans | Mangiferin | Antifungal ointment [49] |
Antiviral | Mango leaf, bark, fruits, flowers | Ho et al. reported antiviral activity of flavonoids against Herpes simplex virus, respiratory syncytial virus, Parainfluenza virus, and Adenovirus [41] | Flavonoids [83] Mangiferin | Â |
Antimalarial | Leaves | Adepiti et al. [27] investigated the in vivo anti-malarial activity of a leaf decoction on Plasmodium berghei infested mice model | Flavonoids Tannins [86] Mangiferin Alkaloids | The study reported 55% P.berghei reduction by the fifth day of treatment |
Anti-halitosis | Mango twig is used as chewing stick | Dandekar and Winnier [54] assessed activity of mango twigs extracts against S. mutans | Flavonoids Tannins Mangiferin | Toothpaste [57], |
Gastro intestinal system ailment | It is used in folk medicine as an astringent, remedy for bowel obstruction, and vomiting | Pacheco-Ordaz [38] assessed the intestinal activity of mango extract | Tannins |