Table 3 Observed responses for softening point (Y1) and percentage drug release after 12 h (Y2) from randomized runs in the BBD
Formulation | Independent variables | Response variables | |||
|---|---|---|---|---|---|
X1 | X2 | X3 | Y1 (°C) | Y2 (%) | |
F1 | 0 | 1 | 1 | 48 | 78.97 |
F2 | 0 | − 1 | − 1 | 46 | 79.83 |
F3 | 1 | − 1 | 0 | 49 | 70.03 |
F4 | − 1 | 0 | 1 | 37 | 75.63 |
F5 | 1 | 1 | 0 | 52 | 69.12 |
F6 | − 1 | 1 | 0 | 38 | 77.68 |
F7 | − 1 | 0 | − 1 | 37 | 77.93 |
F8 | 1 | 0 | 1 | 51 | 80.38 |
F9 | 1 | 0 | − 1 | 50 | 79.44 |
F10 | 0 | 0 | 0 | 47 | 81.76 |
F11 | 0 | 1 | − 1 | 48 | 86.94 |
F12 | − 1 | − 1 | 0 | 35 | 72.68 |
F13 | 0 | 0 | 0 | 46 | 83.66 |
F14 | 0 | 0 | 0 | 47 | 84.91 |
F15 | 0 | − 1 | 1 | 45 | 82.1 |