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Table 4 Physicochemical Characterization of lipstick formulations data

From: In vitro characterization of self-emulsifying drug delivery system-based lipsticks loaded with ketoconazole

Formulation

Melting Point (°C)

Breaking Point (gm)

Spreadability test

Surface anomalies

% Drug content

F1

56 ± 1.02

129 ± 1.71

G

No defects

95.44 ± 1.91

F2

57 ± 0.92

126 ± 1.65

P

Slight cracking

94.13 ± 2.38

F3

59 ± 0.56

130 ± 2.22

G

No defects

93.42 ± 1.77

F4

51 ± 1.34

127 ± 2.61

M

Slight cracking

94.28 ± 2.49

F5

64 ± 0.97

134 ± 1.73

M

No defects

98.22 ± 2.38

F6

52 ± 0.88

128 ± 2.17

P

Cracks

90.63 ± 1.42

F7

53 ± 0.99

127 ± 2.29

P

Slight cracking

93.95 ± 1.56

F8

61 ± 1.41

131 ± 2.15

G

No defects

98.07 ± 1.49

F9

61 ± 0.59

131 ± 1.91

M

Slight cracking

97.26 ± 2.07

F10

55 ± 1.15

130 ± 2.63

G

No defects

94.49 ± 2.26

F11

58 ± 2.1

129 ± 1.02

G

No defects

99.35 ± 1.64

F12

50 ± 0.94

125 ± 1.43

G

No defects

98.91 ± 2.42

F13

56 ± 1.67

128 ± 1.76

M

No defects

99.05 ± 2.2

F14

55 ± 0.87

127 ± 2.12

M

No defects

99.84 ± 1.25

F15

53 ± 0.61

126 ± 2.67

G

No defects

97.64 ± 1.52

  1. All the data are results of three analyses (n = 3), indicated as mean ± SD
  2. Letters ‘G’, ‘M’, and ‘P’ indicates the good, moderate, and poor spreadability of the formulations