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Table 5 ANOVA of the fitted equation for softening point and percentage release after 12 h from lipstick formulation

From: In vitro characterization of self-emulsifying drug delivery system-based lipsticks loaded with ketoconazole

 

Softening point

% Drug release after 12 h

Sum of Squares

df

Mean Square

F-value

Sum of Squares

df

Mean Square

F-value

Model

429.52

9

47.72

168.44

475.64

9

52.85

39.32

A-Beeswax

378.12

1

378.12

1334.56

71.70

1

71.70

53.35

B-Carnauba Wax

15.12

1

15.12

53.38

8.14

1

8.14

6.06

C-Cow Ghee

0.20

1

0.20

0.24

8.12

1

8.12

6.04

Residual

1.42

5

0.2833

 

6.72

5

1.34

 

Lack of Fit

0.7500

3

0.2500

0.7500

0.99

3

0.5629

0.2237

Pure Error

0.6667

2

0.3333

 

1.03

2

0.52

 

Std. Dev

0.5323

   

1.16

   

Adjusted R2

0.9908

   

0.9610

   

Predicted R2

0.9687

   

0.9205

   

R2

0.9967

   

0.9861