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Future Journal of Pharmaceutical Sciences

Table 4 Inhibitory kinetics of stem-bark extract on some enzymes

From: HPLC fingerprint of flavonoids, enzyme inhibition and antioxidant activity of Newbouldia laevis stem-bark: an in vitro and in silico study

Enzyme inhibition

IC50 (mg/mL)

Ki

Acetylcholinesterase

129.46A ± 1.60

3.92a ± 1.04

Butyrylcholinesterase

237.10B ± 0.43

1.63b ± 0.18

Phospholipase A2

169.50C ± 0.21

1.11b ± 0.10

α-Glucosidase

251.04B ± 1.05

2.95a ± 0.35

α-Amylase

243.06B ± 0.47

2.11a ± 0.55

  1. Values with different uppercase are statistically significant (p < 0.05) compared down the enzymes
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