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Table 6 Predicted toxicity analysis

From: HPLC fingerprint of flavonoids, enzyme inhibition and antioxidant activity of Newbouldia laevis stem-bark: an in vitro and in silico study

Phyto-compounds

Predicted LD50 value (mg/kg)

Predicted toxicity class (1–6)

Prediction accuracy (%)

Hepatotoxicity

Immunotoxicity

Cytotoxicity

Carcinogenicity

Mutagenicity

Quercetin

159

3

100

Inactive

Inactive

Inactive

Active

Active

Kaempferol

3919

5

70.97

Inactive

Inactive

Inactive

Inactive

Inactive

Apigenin

2500

5

70.97

Inactive

Inactive

Inactive

Inactive

Inactive

Catechin

10,000

6

100

Inactive

Inactive

Inactive

Inactive

Inactive

Isorhamnetin

5000

5

70.97

Inactive

Active

Inactive

Inactive

Inactive

Naringin

2300

5

70.97

Inactive

Active

Inactive

Inactive

Inactive

Luteolin

3919

5

80.26

Inactive

Active

Inactive

Active

Inactive