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Future Journal of Pharmaceutical Sciences

Table 4 Effect of EATC on LDL level in high-fat diet-induced atherosclerotic model in rats

From: Evaluation of anti-atherosclerotic potential of Tinospora cordifolia in high-fat diet-induced atherosclerosis with associated changes in histological and biochemical parameters on Wistar rats

Exp. group

LDL (mg/dL) 60 days

LDL(mg/dL) 80 days

Normal control (NC)

23.333 ± 3.252

23.333 ± 3.528

Disease control (DC)

135.167 ± 8.252

151.833 ± 6.467

STD (AVT-10 mg/kg)

133.667 ± 5.011

45.000 ± 4.597b*

EATC (100 mg/kg)

150.667 ± 5.777

93.000 ± 4.107a*b*c*

EATC (200 mg/kg)

149.667 ± 2.155

76.500 ± 7.442a*b*c#

  1. As depicted in Table values are expressed as mean ± SEM; n = 6; Data analyzed by One-way ANOVA test followed by Tukey’s multiple test for comparison
  2. NC, normal control; DC, disease control; EATC, ethyl acetate fraction of stem of Tinospora cordifolia
  3. aAs compared with normal control group, bas compared with disease control group, cas compared with standard (Atorvastatin) group, Level of significance †P < 0.05; #P < 0.01; *P < 0.001
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