Future Journal of Pharmaceutical Sciences

Table 9 Effect of EATC on SGPT, SGOT, and ALP level in high-fat diet-induced atherosclerotic model in rats

From: Evaluation of anti-atherosclerotic potential of Tinospora cordifolia in high-fat diet-induced atherosclerosis with associated changes in histological and biochemical parameters on Wistar rats

Exp. group	SGOT (U/L)		SGPT (U/L)		ALP (U/L)
Exp. group	60 days	80 days	60 days	80 days	60 days	80 days
Normal control (NC)	23.500 ± 3.212	24.16 ± 3.390	120.500 ± 3.538	122.66 ± 3.879	91.167 ± 3.038	91.50 ± 3.191
Disease control (DC)	37.833 ± 3.070	47.00 ± 2.933	157.833 ± 2.7623	173.33 ± 2.848	145.667 ± 2.044	159.33 ± 2.824
STD (AVT-10 mg/kg)	43.667 ± 2.231	22.33 ± 1.978^b*	157.167 ± 3.341	127.83 ± 5.546^b*	165.833 ± 1.701	114.33 ± 4.602^a^b
EATC (100 mg/kg)	41.000 ± 2.206	29.33 ± 2.836^b#	166.833 ± 1.641	150.83 ± 1.662^a*^b#c#	154.167 ± 2.496	138.1 ± 2.868^a^b#c
EATC (200 mg/kg)	45.667 ± 2.155	25.16 ± 2.774^b*	155.500 ± 3.658	128.33 ± 3.955^b*	159.333 ± 2.765	124.33 ± 3.547^a^b

As depicted in Table values are expressed as mean ± SEM; n = 6; Data analyzed by One-way ANOVA test followed by Tukey’s multiple test for comparison
NC, normal control; DC, disease control; EATC, ethyl acetate fraction of stem of Tinospora cordifolia; ALP, Alkaline Phosphatase; SGOT, Serum Glutamic-Oxaloacetic Transaminase; SGPT, Serum Glutamic-Pyruvic Transaminase
^aAs compared with normal control group, ^bas compared with disease control group, ^cas compared with standard (Atorvastatin) group, Level of significance †P < 0.05; #P < 0.01; *P < 0.001

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