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Table 2 Curcumin efficacy as an antifungal

From: Emerging therapeutic potential of curcumin in the management of dermatological diseases: an extensive review of drug and pharmacological activities

S. no

Findings of study

Fungal agents used in the study

References

1

Curcumin showed 250–2000 μg/mL range of MIC along with fungicidal action toward species of candida

Ten clinical isolates, four strains of ATCC and 14 candida strains

[72]

2

Photodynamic therapy along with curcumin (40 μM) was utilized in the study. It was able to inhibit 85 percent of the candida species activity and also led to reduction of biomass of the biofilm of all the three fungal agents

C. tropicalis, C. glabrata, C. albicans

[75]

3

Curcumin was administered orally in BALB/c mice in a study done in vivo. It was found more effective in the reduction of fungal infection in comparison with dexamethasone

Oropharyngeal candidiasis

[74]

4

Curcumin was able to show high efficacy and inhibitory action toward these agents

Clinical isolate, fluconazole-resistant strains and 38 strains of Candida

[72]

5

Curcumin was used along with fluconazole which was able to produce a synergistic action and in vitro studies found that it was highly active against C. albicans

C. albicans (Clinically-resistant Isolate)

[100]

6

Cell wall inhibitory agents and curcumin was used which produced a high synergistic action against the cell wall of the fungi leading to its disruption

C. albicans

[65]