Table 1 Experimental design of DTX niosomes and effect on dependent variables
From: Design, development, and evaluation of docetaxel-loaded niosomes for the treatment of breast cancer
Formulation code | Factor 1 | Factor 2 | Response 1 | Response 2 |
|---|---|---|---|---|
Cholesterol (X1) (mg) | Span® 40 (X2) (mg) | Particle size (nm) | EE (%) | |
F1 | 2 | 2 | 444.5 ± 2.5 | 83.56 ± 1.2 |
F2 | 2 | 2.5 | 421.8 ± 1.3 | 76.95 ± 1.3 |
F3 | 2 | 3 | 489.0 ± 0.9 | 66.55 ± 0.4 |
F4 | 2.5 | 2 | 412.0 ± 1.1 | 86.31 ± 0.9 |
F5 | 2.5 | 2.5 | 244.9 ± 0.5 | 97.43 ± 1.2 |
F6 | 2.5 | 3 | 531.6 ± 1.2 | 89.69 ± 1.1 |
F7 | 3 | 2 | 518.0 ± 1.3 | 82.26 ± 0.8 |
F8 | 3 | 2.5 | 346.0 ± 1.7 | 84.37 ± 0.7 |
F9 | 3 | 3 | 391.5 ± 1.4 | 87.65 ± 1.2 |