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Table 3 Linearity data for nateglinide and metformin HCl

From: A stability indicating UPLC method development and validation for the simultaneous estimation of nateglinide and metformin hydrochloride in bulk and tablet dosage form

Sample

Nateglinide

Metformin HCL

Conc. (μg/mL)

Peak area

(Mean ± SD)

Conc. (μg/mL)

Peak Area

(Mean ± SD)

1

7.50

136,455 ± 944

62.50

717,923 ± 4927

2

15.00

266,702 ± 1844

125.00

1,463,602 ± 8622

3

22.50

397,289 ± 2240

187.50

2,085,176 ± 9958

4

30.00

532,591 ± 3722

250.00

2,855,164 ± 12,663

5

37.50

653,582 ± 5679

312.50

3,443,907 ± 30,527

6

45.00

789,578 ± 8785

375.00

4,215,888 ± 36,152

Slope

17,377

18,439

Intercept

6543.4

43,537

R2

0.9998

0.999