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Table 4 Mean ± SD of BA pharmacokinetics parameters for healthy volunteers, geriatrics and cancer patients

From: Characterization, cellular uptake in Caco-2 cells and physiologically based pharmacokinetic modeling of baicalin-loaded solid lipid nanoparticles

Parameters

Healthy volunteers

Geriatrics

Cancer patients

Tmax (h)*

1.58 (1.1–2.3)

1.93 (1.5–2.7)

1.73 (1.5–2.7)

Cmax (ng/mL)

421.46 ± 136.50

431.98 ± 98.80

400.85 ± 109.10

AUC0–24 h (ng/nL h)

1311.09 ± 660.0

1752.16 ± 859.70

1480.79 ± 919.20

  1. *Median (range)