Table 13 Results of the stability study
From: Development and optimization of Ropinirole loaded self-nanoemulsifying tablets
Test parameter | Acceptance criteria | Sampling time in days | ||
|---|---|---|---|---|
0 | 15 | 30 | ||
Liquid SNEDDS | ||||
Rate of emulsification | NMT 15% from the initial value | Complied | No change | No change |
Transparency | NLT 90% | 98.89 ± 0.1 | 98.67 ± 1.2 | 99.10 ± 0.98 |
Drug precipitation | Not before 24 h | Complied | Complied | Complied |
SNEDDS tablet | ||||
Description | White-colored round biconvex tablet | Complied | No change | No change |
Diameter | 12 mm | Complied | No change | No change |
Thickness | 4.2 mm | Complied | No change | No change |
Disintegration time | NMT 15% | 4.25 min | 5.61 min | 7.2 min |
Content uniformity | 2 mg ± 15% | 1.98 ± 0.45 | 1.96 ± 0.12 | 1.92 ± 1.2 |