Table 4 Solubility of Ropinirole in various Solvents
From: Development and optimization of Ropinirole loaded self-nanoemulsifying tablets
Oil (1 ml) | Solubility (mg/mL) (Mean ± SD), n = 3 | Surfactant | Solubility (mg/mL) (Mean ± SD), n = 3 | Co-surfactant | Solubility (mg/mL) (Mean ± SD), n = 3 |
|---|---|---|---|---|---|
Capmul MCM C8 | 5.9 ± 0.01 | Span 20 | 1.8 ± 0.20 | Transcutol HP | 5.4 ± 0.004 |
Miglyol 812 N | 2.6 ± 0.002 | Span 80 | 9 ± 0.21 | Acrysol EL135 | 2.2 ± 0.34 |
Castor oil | 2.1 ± 0.002 | Tween 20 | 5.9 ± 0.23 | Acconon MC8 | 1.7 ± 0.63 |
Captex 355 | 1.8 ± 0.56 | Tween 40 | 1.9 ± 0.15 | – | – |
Capmul MCM EP | 11.6 ± 0.57 | – | – | – | – |
Captex 200 P | 1.7 ± 0.28 | – | – | – | – |
Labrafac PG | 2.2 ± 0.32 | – | – | – | – |