Table 7 Results of Box–Behnken design
From: Development and optimization of Ropinirole loaded self-nanoemulsifying tablets
Batch | A | B | C | Y1 (Droplet size in nm) | Y2 (Rate of emulsification in a s) |
|---|---|---|---|---|---|
ROP23 | 0 | 1 | − 1 | 35.78 ± 0.56 | 18 ± 0.12 |
ROP24 | 0 | − 1 | 1 | 41.32 ± 1.01 | 76 ± 0.13 |
ROP25 | 1 | 0 | 1 | 169.9 ± 0.54 | 35 ± 0.06 |
ROP26 | 0 | 1 | 1 | 39.7 ± 0.52 | 18 ± 0.65 |
ROP27 | 1 | 1 | 0 | 199.1 ± 0.48 | 18 ± 0.43 |
ROP28 | 0 | − 1 | − 1 | 42.78 ± 01.26 | 71 ± 0.56 |
ROP29 | − 1 | 0 | − 1 | 21.39 ± 2.61 | 19 ± 0.22 |
ROP30 | − 1 | 1 | 0 | 50.08 ± 1.45 | 22 ± 0.45 |
ROP31 | − 1 | − 1 | 0 | 40.15 ± 2.32 | 57 ± 0.56 |
ROP32 | 1 | 0 | − 1 | 201.3 ± 1.02 | 35 ± 0.45 |
ROP33 | − 1 | 0 | 1 | 93.34 ± 1.76 | 37 ± 0.47 |
ROP34 | 0 | 0 | 0 | 23.8 ± 2.34 | 19 ± 0.67 |
ROP35 | 1 | − 1 | 0 | 233.2 ± 2.18 | 75 ± 0.87 |