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Future Journal of Pharmaceutical Sciences

Table 1 Validation parameters of the spectrophotometric determination of SOF, LDV, and PAR

From: Simultaneous spectrophotometric determination of recombined sofosbuvir, ledipasvir and paracetamol together as commonly repurposed drugs for COVID-19 treatment

Parameter

SOF(first der. 247.2 nm)

LDV(zero order 333 nm)

PAR(first der. 260.8 nm)

Range(μg/mL)

8–60

4–22

2–14

Slope

0.007

0.055

0.041

Intercept

− 0.007

-0.024

0.008

Correlation coefficient (r)

0.9997

0.9998

0.9998

Precision (RSD %)

Intraday*

0.715

1.268

1.759

Interday*

0.597

1.1504

1.306

  1. *Relative standard deviation (n = 3), average of three different concentrations of SOF, LDV, and PAR
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