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Table 3 Determination of the studied drugs in laboratory prepared mixtures by the proposed methods

From: Simultaneous spectrophotometric determination of recombined sofosbuvir, ledipasvir and paracetamol together as commonly repurposed drugs for COVID-19 treatment

Binary mixture SOF: LDV: PAR ratios

%Recoverya

SOF(first derivative) (%)

LDV(zero order) (%)

AR(first derivative) (%

4: 0.9(+ spiking 10ug/mL):5

100.92

101.86

101.18

2: 1:1

100.47

100.21

98.23

1: 2:1

99.59

100.74

98.71

Mean ± SD

100.33 ± 0.67

100.93 ± 0.84

99.38 ± 1.58

  1. aAverage of three determinations