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Future Journal of Pharmaceutical Sciences

Table 3 Set ranges of MODR region

From: Development of a robust and reliable reverse-phase high-performance liquid chromatography (RP-HPLC) method using analytical quality by design principles for the accurate determination of esculin in its bulk form

Name

Goal

Lower limit

Upper limit

Importance

A: Methanol (%) in mobile phase

Maximize

40

50

3

B: Flow rate

Is in range

0.8

1.2

3

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