Table 3 Functional enrichment of network obtained from STRING database
| Â | GO-term | Description | Count in network | Strength | False discovery rate |
|---|---|---|---|---|---|
Biological process (Gene Ontology) | GO:0032543 | Mitochondrial translation | 6 of 114 | 1.2 | 0.0364 |
Cellular Component (Gene Ontology) | GO:0005739 | Mitochondrion | 16 of 1611 | 0.48 | 0.0102 |
GO:0005743 | Mitochondrial inner membrane | 12 of 480 | 0.88 | 5.51e-05 | |
GO:0005761 | Mitochondrial ribosome | 5 of 87 | 1.24 | 0.0038 | |
GO:0031966 | Mitochondrial membrane | 14 of 722 | 0.77 | 5.62e-05 | |
GO:0098798 | Mitochondrial protein complex | 10 of 262 | 1.06 | 3.44e-05 |
| Â | Pathway | Description | Count in network | Strength | False discovery rate |
|---|---|---|---|---|---|
KEGG Pathways | hsa05010 | Alzheimer disease | 7 of 355 | 0.77 | 0.0152 |
hsa05012 | Parkinson disease | 7 of 240 | 0.94 | 0.0058 | |
hsa05014 | Amyotrophic lateral sclerosis | 7 of 352 | 0.78 | 0.0152 | |
hsa05016 | Huntington disease | 7 of 298 | 0.85 | 0.0074 | |
hsa05020 | Prion disease | 7 of 265 | 0.9 | 0.0058 |