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Fig. 19 | Future Journal of Pharmaceutical Sciences

Fig. 19

From: Neuroprotective action of Smilax china ethanolic bark extract in treatment of a prominent aging disorder: Parkinson’s disease induced by rotenone

Fig. 19

Histopathological examination of substantia nigra: a Group-1 (Control): Normal neuronal density and normal brain architecture no abnormality detected. b Group-2 (Induction): Major degradation of neurons (red arrow) and infiltration of vacuolated neutrophils (Black arrow). c Group-3 (Standard): Minimal neurofibrillary tangles (black arrow). d Group-4 (Treatment-I): Minimal degradation of neurons (Red arrow) and infiltration of vacuolated neutrophils (Black arrow). e Group-5 (Treatment-II): Minimal infiltration of vacuolated neutrophils (Black arrow) and reduced necrosis H & E, (hematoxylin and eosin) 10X

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