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Table 10 Effect of ethanolic extract of Smilax china during acute toxicity study

From: Neuroprotective action of Smilax china ethanolic bark extract in treatment of a prominent aging disorder: Parkinson’s disease induced by rotenone

S. No

Response

Control

Dose per kg/body weight

2000 mg/kg

1

Restlessness

 − Ve

 − Ve

2

Alertness

Usual

Usual

3

Righting reflux

Usual

Usual

4

Tremors

 − Ve

 − Ve

5

Grooming

Usual

Usual

6

Pupil

Usual

Usual

7

Pain response

 − Ve

 − Ve

8

Water intake

Usual

Usual

9

Food intake

Usual

Usual

10

Salivation

Usual

Usual

11

Writhing

Usual

Usual

12

Urination

Usual

Usual

13

Torch response

 − Ve

 − Ve

14

Skin color

 − Ve

 − Ve

15

Gripping

Usual

Usual

16

Fur shedding/density

 − Ve

 − Ve

17

Convulsion

 − Ve

 − Ve

18

Mortality

Usual

Usual

19

Touch response

Usual

Usual