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Table 15 The catalepsy score was recorded after 15th days after PD was induced in male Wistar rats using a bar test for catalepsy

From: Neuroprotective action of Smilax china ethanolic bark extract in treatment of a prominent aging disorder: Parkinson’s disease induced by rotenone

Time interval (min)

Catalepsy score in seconds

    

Group-1 (Control)

Group-2 (Induction)

Group-3 (Standard)

Group-4 (Treatment-I)

Group-5 (Treatment-II)

0

2.75 ± 0.24

6.38 ± 0.37

4.46 ± 0.21

5.32 ± 0.28

5.43 ± 0.33

30

2.82 ± 0.21

31.28 ± 4.91a

23.43 ± 4.12*

24.26 ± 2.67*

20.8 ± 2.97*

60

2.66 ± 0.16

131.68 ± 5.08a

32.07 ± 4.78*

19.39 ± 2.08*

19.01 ± 2.38*

120

2.75 ± 0.15

96.26 ± 6.07a

32.60 ± 3.62*

20.38 ± 1.40*

20.45 ± 4.07*

180

2.86 ± 0.13

73.45 ± 5.04a

27.30 ± 3.24*

21.11 ± 1.38*

17.58 ± 4.23*

  1. Average standard error of the mean; sample size = 6. The use of one-way ANOVA: Multiple comparisons using the Tukey–Kramer method: ap < 0.005 in comparison with normal control; *p < 0.005 in comparison with the Induction group. A significant improvement in the catalepsy score was seen in the treatment group after 15 days of treatment when compared with the induction and control group