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Table 19 The block test was used to record the catalepsy score 21st days after Parkinson's disease was induced in male Wistar rats

From: Neuroprotective action of Smilax china ethanolic bark extract in treatment of a prominent aging disorder: Parkinson’s disease induced by rotenone

Time interval (min)

Catalepsy score in seconds

    

Group-1 (Control)

Group-2 (Induction)

Group-3 (Standard)

Group-4 (Treatment-I)

Group-5 (Treatment-II)

0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

30

0.0 ± 0.0

2.58 ± 0.28a

0.50 ± 0.13*

0.80 ± 0.26*

0.74 ± 0.08*

60

0.0 ± 0.0

3.48 ± 0.00a

0.58 ± 0.13*

1.06 ± 0.18*

0.78 ± 0.17*

120

0.0 ± 0.0

3.54 ± 0.08a

0.65 ± 0.11*

0.87 ± 0.16*

0.58 ± 0.15*

180

0.0 ± 0.0

3.69 ± 0.07a

0.60 ± 0.09*

0.80 ± 0.07*

0.47 ± 0.17*

  1. Average standard error of the mean; sample size = 6. The use of one-way ANOVA: Tukey–Kramer test for multiple comparisons: ap < 0.001 in comparison with normal control; *p < 0.001 in comparison with the Induction group. Post 21 days of regular treatment the catalepsy score from the block test showed statistically significant improvement in treated groups