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Table 2 Dosing of acute oral toxicity of ethanolic extract of Smilax china (as per OECD guidelines 423)

From: Neuroprotective action of Smilax china ethanolic bark extract in treatment of a prominent aging disorder: Parkinson’s disease induced by rotenone

S. No

Group

Dosing

Observation period

No. of Animals required (n)

1

Control

Vehicle

4 h, 72 h, 7 days, 14 days

3

2

Treatment-I

Drug extract 1000 mg/kg

4 h, 72 h, 7 days, 14 days

3

3

Treatment-II

Drug extract 2000 mg/kg

4 h, 72 h, 7 days, 14 days

3

   

Total

9