Future Journal of Pharmaceutical Sciences

Table 1 Targets protein binding coordinates

From: Probing the multitargeting potential of n-hexane fraction of Gongronema latifolium leaves in neurodegeneration via in vitro, GC–MS and in silico studies

Dimensions	Aβ fibrils (Å)	BACE-1 (Å)	hAChE (Å)	bAChE (Å)
Center_x	0.55	67.91	− 13.48	2.54
Center_y	0.02	48.43	− 43.40	− 9.30
Center_z	− 8.25	9.57	27.61	− 14.86
Size x	52.76	16.72	24.78	18.53
Size y	22.91	16.24	16.73	21.94
Size z	32.81	19.95	19.87	17.05

Blind docking of the ligands was performed against Aβ fibrils, while targeted docking was performed against BACE-1, hAChE and hBChE

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