Table 3 Outcomes of stability studies of optimized CA-NGG nanoformulation
Time | 0 Month | 1 Month | 2 Month | 3 Month | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameter | 4 °C | 25 °C | 45 °C | 4 °C | 25 °C | 45 °C | 4 °C | 25 °C | 45 °C | 4 °C | 25 °C | 45 °C |
EE (%) | 62.47 ± 4.23 | 62.47 ± 4.23 | 62.47 ± 4.23 | 61.87 ± 5.45 | 52 ± 4.68 | 49 ± 3.98 | 60.43 ± 6.09 | 48 ± 4.51 | 30 ± 2.56 | 59.45 ± 5.34 | 30 ± 2.16 | 15 ± 1.03 |
Particle size (nm) | 209.4 ± 20.46 | 209.4 ± 20.46 | 209.4 ± 20.46 | 215.6 ± 20.98 | 240.67 ± 21.45 | 320.98 ± 5.43 | 221.9 ± 20.24 | 310.67 ± 29.68 | 874.09 ± 70.98 | 235.79 ± 20.89 | 490.9 ± 30.98 | 3065.57 ± 210.98 |
Physical appearance | Clear | Clear | Clear | Clear | Cloudy to slightly light yellow | Pastel yellow with small bunches of particles discrete on shaking | Clear | Pastel yellow with small bunches of particles discrete on shaking | Brownish color formulation with bunches do not discrete on shaking | Cloudy to slightly light yellow | Brownish color suspension with bunches of particles discrete on shaking | Brownish color formulation with bunches do not discrete on shaking |