Table 1 Composition of tablets (SR and IR) containing febuxostat
From: Optimizing pulsatile release of febuxostat for managing gout flares: a chronotherapeutic approach
Batch | Febuxostat/soluplus (mg) | HPMC K15M (mg) | HPMC K100M (mg) | Lactose (mg) | Crospovidone (mg) | Sodium starch glycolate (mg) |
|---|---|---|---|---|---|---|
S1 | 75 | 75 | – | – | – | – |
S2 | 75 | – | 75 | – | – | – |
S3 | 75 | 37.5 | 37.5 | – | – | – |
S4 | 75 | 37.5 | – | 37.5 | – | – |
R1 | 45 | – | – | 45 | 10 | – |
R2 | 45 | – | – | 45 | – | 10 |