Table 4 Regression statistical analysis for the observed responses of 32 full factorial design
From: Optimizing pulsatile release of febuxostat for managing gout flares: a chronotherapeutic approach
Response Y1 | Response Y2 | Response Y3 | |
|---|---|---|---|
R2 | 0.8314 | 0.8794 | 0.9937 |
Adjusted R2 | 0.7751 | 0.8392 | 0.9831 |
Predicted R2 | 0.6176 | 0.7006 | 0.9331 |
Adeq precision | 10.6754 | 13.1711 | 28.0558 |
PRESS value | 134.69 | 1.17 | 0.8568 |
F value | 14.79 | 21.88 | 94.20 |
p value | 0.0048 | 0.0018 | 0.0017 |
Coefficients | |||
β0 | + 67.17 | + 5.12 | + 9.41 |
β1 (X1) | − 5.80 | + 0.5833 | − 1.35 |
β2 (X2) | + 3.90 | + 0.4833 | − 0.5333 |
β12 (X1X2) | – | – | − 0.1500 |
β3 (X12) | – | – | − 0.0167 |
β4 (X22) | – | – | + 0.0333 |