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Table 1 Binding and thermodynamic properties of the CBZ-BSA and CBZE-BSA systems

From: Spectroscopic study of drug–drug interactions: influence of two over-the-counter drugs on the albumin binding affinities of carbamazepine and its major metabolite

Interactions

25 °C

37 °C

\(\Delta H\) (KJ/mol

\(\Delta S\) (KJ/mol

ln \(K_{f}\)

\(- \Delta G\) (KJ/mol

ln \(K_{f}\)

\(- \Delta G\) (KJ/mol

CBZ

10.276

25.460

10.436

25.857

− 8.445

0.002

CBZE

12.658

31.361

13.017

32.251

− 8.550

0.001