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Table 2 Ln Kf and n of ligand–protein systems in the presence and absence of competing drugs

From: Spectroscopic study of drug–drug interactions: influence of two over-the-counter drugs on the albumin binding affinities of carbamazepine and its major metabolite

Complex

ln \(K_{f}\)

n

R

CBZ-BSA

10.276

1.11

0.9

CBZ-BSA-paracetamol

13.602

1.94

0.92

CBZ-BSA-ascorbic acid

13.444

1.95

0.64

CBZE-BSA

12.658

1.27

0.98

CBZE-BSA-paracetamol

10.478

2.11

0.96

CBZE-BSA-ascorbic acid

13.442

0.56

0.91

  1. *R is correlation coefficient