Future Journal of Pharmaceutical Sciences

Table 2 Accuracy results for UHPLC method for the quantification of SOF, LDV and PAR in bulk

From: Rapid and validated UHPLC method for simultaneous determination of sofosbuvir, ledipasvir and paracetamol as commonly repurposed drugs for COVID-19 treatment: application in spiked human plasma

SOF			LDV			PAR
Taken µg/mL	Found µg/mL	Recovery, %^a	Taken µg/mL	Found µg/mL	Recovery, %^a	Taken µg/mL	Found µg/mL	Recovery, %^a
15	15.26	100.51	5	7.91	98.91	2	1.99	99.77
25	24.85	99.41	15	14.89	99.31	6	6.04	100.81
40	40.77	100.07	18	17.842	99.12	18	18.09	100.50
	Mean ± SD			Mean ± SD			Mean ± SD
	99.99 ± 0.554			99.11 ± 0.197			100.36 ± 0.535

^aAverage of three determinations

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