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Future Journal of Pharmaceutical Sciences

Table 3 Accuracy results for UHPLC method for the quantification of SOF and LDV in spiked human plasma

From: Rapid and validated UHPLC method for simultaneous determination of sofosbuvir, ledipasvir and paracetamol as commonly repurposed drugs for COVID-19 treatment: application in spiked human plasma

SOF

LDV

Taken µg/mL

Found µg/mL

Recovery, %a

Taken µg/mL

Found µg/Ml

Recovery, %a

8

7.77

97.19

7

6.88

98.32

18

17.77

98.75

14

13.38

95.58

25

24.87

99.49

18

17.29

96.05

 

Mean ± SD

  

Mean ± SD

 
 

98.48 ± 1.174

  

96.65 ± 1.465

 
  1. aAverage of three determinations
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