From: Rapid and validated UHPLC method for simultaneous determination of sofosbuvir, ledipasvir and paracetamol as commonly repurposed drugs for COVID-19 treatment: application in spiked human plasma
Binary mixture SOF: LDV:PAR ratios
%Recoverya
SOF
LDV
PAR
4: 0.9:5
99.61%
99.86%
100.52%
2: 1:1
98.99%
100.00%
98.68%
1: 2:1
100.31%
98.78%
99.26%
Mean ± SD
99.64 ± 0.65
99.55 ± 0.66
99.48 ± 0.93