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Table 2 Toxicity types and grades among the studied patients

From: Down-regulation of MSH3 and MSH6 genes in female breast cancer patients receiving taxane-based therapy

Toxicity type

 

Cases

N = 105

no. (%)

Number of toxicities

(% out of total cases)

No symptom

One symptom

2

3

4

5–9 symptoms

26 (24.8)

14 (17.7)

22 (27.8)

26 (33.0)

9 (11.4)

8 (10.0)

Diarrhea

Grade:

(% of positive cases)

Yes

1

2

3

21 (20.0)

6 (28.6)

8 (38.1)

7 (33.3)

Gastritis

Grade:

(% of positive cases)

Yes

1

2

3

19 (18.1)

11 (57.9)

5 (26.3)

3 (15.8)

Fatigue

Grade:

(% of positive cases)

Yes

1

3

22 (21.0)

20 (90.9)

2 (9.1)

Skin rash

Grade:

(% of positive cases)

Yes

1

3 (2.9)

2 (66.7)

Nail damage

Yes (all grade 1)

2 (1.9)

Nausea

Grade:

Yes

1

2

3

19 (18.1)

10 (52.6)

8 (42.1)

1 (5.3)

Vomiting

Grade:

(% of positive cases)

Yes

1

2

3

17 (16.2)

11 (64.7)

5 (29.4)

1 (5.9)

Stomatitis

Yes (grade1)

1 (1.0)

Peripheral neuropathy

Grade:

(% of positive cases)

Yes

1

2

3

4

61 (58.1)

24 (39.3)

33 (54.1)

3 (4.9)

1 (1.6)

Dyspnea

Grade:

(% of positive cases)

Yes

1

2

8 (7.5)

7 (87.5)

1 (12.5)

Bone pain

Grade:

(% of positive cases)

Yes

1

2

3

60 (57.1)

43 (71.7)

13 (21.7)

4 (6.7)