Table 4 Pharmacokinetic parameters obtained from Plasma concentration vs time data for an oral dose of Montek 10 and MTS ChrDDS

1

C_max (ng/ml)

490.16 ± 33.95*

648.29 ± 121.63*

2

T_max (h)

9 ± 0.5*

2 ± 0.9*

3

AUC_0–24 (ng h/ml)

4958.51 ± 418.29*

2181.65 ± 309.18*

4

AUC_0-∞ (ng h/ml)

6094.84 ± 531.11*

3486.36 ± 413.61*

5

T_1/2 (h)

7.27 ± 0.71*

2.37 ± 1.04*

6

Mean residence time (MRT) (h)

14.08 ± 1.21*

2.39 ± 1.11*

7

V_d (ml)

1.204 ± 0.18*

0.684 ± 0.11*

8

CL (ml/h)

0.112 ± 0.05*

0.200 ± 0.08*

9

T_last (h)

24*

4.5*