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Future Journal of Pharmaceutical Sciences

Table 5 Stability studies of MTS-loaded developed and optimized ChrDDS

From: IVIVC assessment, pharmacokinetic evaluation, and X-ray radiography mapping of Novel Parteck® SRP 80 and hypromellose-loaded LTD4 receptor antagonist chronosystem

S. no.

Parameters (n = 3)

0 month

3 months

6 months

1

Cumulative percentage release in 23 h

95.61 ± 0.10*

96.27 ± 0.08*

96.91 ± 0.06*

2

Percentage drug content (%)

100.04 ± 0.013*

99.62 ± 0.011*

99.12 ± 0.06*

3

Disintegration time in pH 6.8 (minutes)

5.10 ± 0.02*

4.99 ± 0.01*

4.87 ± 0.02*

4

Similarity factor

–

87.92 ± 0.015

89.93 ± 0.015

  1. *p value > 0.999 statistically similar
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