Chlorogenic acid-optimized nanophytovesicles: a novel approach for enhanced permeability and oral bioavailability

Future Journal of Pharmaceutical Sciences

Table 2 Predicted and observed values for the check point formulation analysis with CGA 90 H NPVs and CGA S100 NPVs

Formulation	Response	Predicted values	Observed values*	(%) Bias
CGA 90H NPVs	Partition coefficient	0.869	0.881 ± 0.48	− 1.38
CGA 90H NPVs	Entrapment efficiency (%)	93.3	95.7 ± 0.56	− 2.57
CGA S100 NPVs	Partition coefficient	0.927	0.942 ± 0.29	− 1.61
CGA S100 NPVs	Entrapment efficiency (%)	86.31	88.5 ± 0.66	− 2.53