Fig. 3
From: Peptide-modified PAMAM-based bone-targeting RNA delivery system
Biocompatibility and gene silencing ability of PS nanoparticles. Cytotoxic effect of different concentrations of PS and PEI on different cell lines using the MTT assay after 24 h of incubation; A MC3T3-E1 cell line; B RAW 264.7 cell line; and C C3H10T1/2 cell line. All data are shown as mean ± SD, n = 3. A student’s t-test was used to compare the differences between the two groups. *P < 0.05, **P < 0.01, and ****P < 0.0001 vs. PEI. (PS: SDSSD-modified PAMAM; PEI: Polyethylenimine)