Fig. 7
From: Peptide-modified PAMAM-based bone-targeting RNA delivery system
The mechanical properties of the femur. A Three-point bending measurement of maximum force in femurs of OVX, PS + NC, and PS + RNA group mice demonstrating force-resistance in PS + RNA group compared to OVX and PS + NC groups. B Three-point bending measurement of stress in femurs of OVX, PS + NC, and PS + RNA group mice, indicating higher force-resistance of the femurs from PS + RNA. C Three-point bending measurement of elasticity modulus in femurs of OVX, PS + NC, and PS + RNA group mice, showing higher modulus of elasticity of PS + RNA group mice femurs. A student’s t-test was used to compare the differences between the two groups. Data are shown as mean ± SD, n = 3. *P < 0.05 **P < 0.01 vs. OVX mice. (PS + NC: SDSSD-modified PAMAM + Negative Control; PS + RNA: SDSSD-modified PAMAM + Antagomir 138-5p; ns: not significant)