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Table 8 Percentage recovery of LTB and BCA after different stress conditions

From: QbD-driven RP-HPLC method for novel chemo-herbal combination, in-silico, force degradation studies, and characterization of dual drug-loaded polymeric and lipidic nanocarriers

Stress conditions

Sample treatment

LTB % recovery*

BCA % recovery*

Acidic hydrolysis

0.1N HCL

97.39 (± 8.43)

94.7 (± 6.28)

Basic hydrolysis

0.1N HCL

57.79 (± 7.9)

78 (± 3.17)

Neutral hydrolysis

H2O

102.5 (± 1.78)

85.52 (± 6.68)

Oxidation

H2O2

59.25(± 3.9)

92.7 (± 5.26)

  1. *Data expressed as mean ± SD, n = 3