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Table 4 Analytical data obtained from enzyme inhibition analyses

From: Inhibitory capacity of extracts and main constituents of hop flowers

Samples

Inhibition assays

Hydroxyl radical n = 2 IC50—µg/mL (RSD%)

Uric acid n = 2 IC50—µg/mL (RSD%)

α-glucosidase n = 3 IC50—µg/mL (RSD%)

Acetylcholinesterase (mm)

ME

HE

ME

HE

ME

HE

ME

HE

(I) Commercial pellets and Brazil cones

Herkules

1,494.345 (5.694)

2,276.029 (21.696)

2,446.075 (2.347)

*

239.344 (6.100)

177.182 (2.729)

**

9

Saaz

*

*

*

*

90.990 (12.430)

313.816 (12.840)

**

7

Chinook-1

2,889.708 (2.718)

2,457.315 (2.115)

2,437.772 (4.222)

*

35.339 (3.873)

127.091 (3.662)

**

8

(II) standards

ICE-4

2,957.723 (18.782)

5,213.415 (4.006)

183.081 (2.934)

6

Xanthohumol

225.241 (7.802)

*

13.184 (10.047)

**

Mangiferin

711.433 (15.154)

521.804 (14.416)

Acarbose

370.540 (2.871)

Eserine

9

  1. RSD relative standard deviation, IC50 inhibitory concentration 50%, mm millimeter, ME methanol extract, HE hexane extract
  2. *Activity less than 50% in the analyzed concentrations
  3. **White halo formation was not observed in the acetylcholinesterase inhibition assay