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Table 2 Variables in 32 factorial design

From: Nanoemulsion drug delivery system loaded with imiquimod: a QbD-based strategy for augmenting anti-cancer effects

Independent variable

Levels used

− 1

0

+ 1

X1: % Oil concentration

15

18

21

X2: % Smix concentration

47

54

61

Response: dependent variable

 Y1 Globule size in nm

Minimum

  

 Y2 Zeta potential in mV

Maximum

 Â