Table 12 Pharmacokinetic studies of Olanzapine and Samidorphan
Pharmacokinetic parametersa | Olanzapine | Samidorphan |
|---|---|---|
AUC0–t (ng h/ml) | 265 ± 2.841 | 75 ± 0.988 |
Cmax (ng/ml) | 18.7 ± 0.134 | 18.4 ± 0.111 |
AUC0–∞ (ng h/ml) | 265 ± 1.427 | 75 ± 1.024 |
T1/2 (h) | 30 ± 0.41 | 10 ± 0.12 |
Tmax (h) | 5 ± 0.2 | 2 ± 0.15 |