Future Journal of Pharmaceutical Sciences

Table 7 Precision and accuracy results of Olanzapine and Samidorphan in rabbit plasma

From: Bioanalytical method development and validation for the simultaneous estimation of Olanzapine and Samidorphan in rabbit plasma by using HPLC–MS/MS and application to pharmacokinetic study

Matrix	Sample	Olanzapine			Samidorphan
		Accuracy bias (%)	Precision RSD (%)		Accuracy bias (%)	Precision RSD (%)
		Accuracy bias (%)	Intra-day	Inter-day	Accuracy bias (%)	Intra-day	Inter-day
Plasma	LLOQC	− 0.74	2.92	− 0.88	− 0.85	1.67	2.12
	LQC	1.11	0.46	1.23	0.89	0.21	0.17
	MQC	0.69	0.15	0.47	0.72	0.13	0.22
	HQC	0.59	0.27	0.06	0.66	0.49	0.58

Back to article page