Table 1 Variables and levels for CCD
Factor | Levels | ||
|---|---|---|---|
Independent variables | 1 | 0 |  − 1 |
Concentration of lipid blend (% w/w) (X1) | 6 | 4 | 2 |
Concentration of surfactant (% w/v) (X2) | 4 | 3 | 2 |
Dependent variables | Constraints | ||
P-size (nm)(Y1) | Minimize | ||
PdI (Y2) | Minimum | ||
Zeta potential (mV) (Y3) | In range | ||