Table 6 Drug NCs with approval of commercialization
From: Nanocrystals: an emerging paradigm for cancer therapeutics
Drug | Product | Method of manufacturing | Route | Indication |
|---|---|---|---|---|
Cabotegravir/rilpivirine | Cabenuva | Media milling | I.M | AIDS |
Meloxicam | Anjeso | Media milling | I.V | Analgesics |
Aripiprazole Auroxil | Aristada | High pressure homogenization | I.M | Schizophrenia |
Paliperidone Palmitate | Invega Trinza | HPH | I.M | Schizophrenia |
Dantrolene sodium | Ryanodex | Media milling | I.V | Malignant hyperthermia |
Nepafenac | Ilevro | Media milling | Drops | Analgesic and anti-inflammatory |
Theophylline | Theodur | Media milling | Oral | Bronchiectasis |
Naproxen sodium | Naprelan | Media milling | Oral | Anti-inflammatory |
Fenofibrate | Triglide | HPH | Oral | Reduce Cholesterol/Triglycerides |
Megestrol acetate | Megace ES | We media milling | oral | Appetite stimulation |
Cannabinoid | Cesamet | Co-precipitation | Oral | Nausea and vomiting |
Aprepitant | Emend | Wet media milling | Oral | Antiemetic |
Tizanidine | Zanaflex | Wet media milling | Oral | Muscle relaxant |
Diltiazem | Herbesser | Media milling | Oral | Angina |
Morphine sulfate | Avinza | Media milling | Oral | analgesia |
Methyl phenidate | Ritalin Focalin | Media milling | Oral | Attention Deficit Hyperactivity Disorder |
Sirolimus | Rapamune | We media milling | Oral | Immune suppression |