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Table 3 Determination of CAR & IVA in tablet dosage form by the proposed methods and application of standard addition technique

From: A unique revolutionary eco-friendly spectrophotometric technique for solving the spectral overlap in the determination of carvedilol and ivabradine in their binary combination: stability study

Sample

CAR (mean% ± SD)

Method

RD

FDW-SS

CC-SS

ITAD-RS

Carivalan®

90.40 ± 0.69

97.95 ± 0.99

97.75 ± 0.51

101.63 ± 1.56

Batch No.29044

99.83 ± 0.40

99.83 ± 1.19

99.48 ± 0.81

98.93 ± 1.37

Standard addition

Sample

IVA (mean ± SD %)

Method

RD

FDW-SS

CC-SS

ITAD-RS

Carivalan®

98.17 ± 0.58

98.75 ± 1.14

100.07 ± 1.98

97.87 ± 0.38

Batch No.29044

Standard addition

100.50 ± 1.39

98.75 ± 0.43

100.71 ± 0.26

99.25 ± 1.15